Jump to main content
Jump to site search

Issue 18, 2019
Previous Article Next Article

An on-demand micro/nano-convertible channel using an elastomeric nanostructure for multi-purpose use

Author affiliations

Abstract

Recently, nanochannels have been widely adopted in microfluidic systems, especially for biosensing and bio-concentrators. Here, we report an on-demand micro/nano-convertible channel, which consists of a simple configuration of elastic nanostructure underneath a single microchannel. By the degree of pressure applied by a pushrod, the microchannel starts to compress into a size-tunable micro- or nano-porous channel. In this approach, under an electric field, we have successfully derived the electrokinetic characteristics of three different regimes: (1) microchannel regime, (2) microporous regime, and (3) nanochannel regime. Utilizing the practical advantage of the transition between regimes with its low cost and easy integration, we demonstrate the pre-concentration and label-free sensing of DNA using a single on-demand convertible channel. Moreover, we demonstrate an ionic diode by applying asymmetric pressure on the elastic nanostructure to create an asymmetric geometry. We believe that the on-demand convertible channel holds potential for promising applications in bioanalytical and iontronic fields.

Graphical abstract: An on-demand micro/nano-convertible channel using an elastomeric nanostructure for multi-purpose use

Back to tab navigation

Supplementary files

Article information


Submitted
14 Jun 2019
Accepted
29 Jul 2019
First published
30 Jul 2019

Lab Chip, 2019,19, 2958-2965
Article type
Communication

An on-demand micro/nano-convertible channel using an elastomeric nanostructure for multi-purpose use

H. J. Kwon, S. K. Hong, M. Lee and G. Lim, Lab Chip, 2019, 19, 2958
DOI: 10.1039/C8LC00997J

Social activity

Search articles by author

Spotlight

Advertisements