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Issue 15, 2019
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Non-spherical polymersomes: formation and characterization

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Polymersomes are self-assembled hollow membrane sacs that are not only able to encapsulate hydrophobic and/or hydrophilic molecules, but also possess exceptional chemical and physical stability, structural versatility, and surface modifiability. For the above reasons, polymersomes have in recent years emerged as a powerful tool for a wide range of applications in the fields of biomimicry and drug delivery. The full potential of polymersomes, however, has yet to be harnessed due to a lack of appreciation of existing shape control methods. This very much contrasts the field of inorganic nanoparticle synthesis where non-spherical hollow metal nanoparticles are routinely prepared and used. Here, we summarize recent efforts over the past decade to study the morphological transformation of conventionally spherical polymersomes into non-spherical polymersomes.

Graphical abstract: Non-spherical polymersomes: formation and characterization

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Article information

14 Apr 2019
First published
12 Jun 2019

Chem. Soc. Rev., 2019,48, 4019-4035
Article type
Tutorial Review

Non-spherical polymersomes: formation and characterization

C. K. Wong, M. H. Stenzel and P. Thordarson, Chem. Soc. Rev., 2019, 48, 4019
DOI: 10.1039/C8CS00856F

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