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Issue 31, 2019
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Rational design of an improved transglucosylase for production of the rare sugar nigerose

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Abstract

The sucrose phosphorylase from Bifidobacterium adolescentis (BaSP) can be used as a transglucosylase for the production of rare sugars. We designed variants of BaSP for the efficient synthesis of nigerose from sucrose and glucose, thereby adding to the inventory of rare sugars that can conveniently be produced from bulk sugars.

Graphical abstract: Rational design of an improved transglucosylase for production of the rare sugar nigerose

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Publication details

The article was received on 25 Feb 2019, accepted on 26 Mar 2019 and first published on 26 Mar 2019


Article type: Communication
DOI: 10.1039/C9CC01587F
Chem. Commun., 2019,55, 4531-4533

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    Rational design of an improved transglucosylase for production of the rare sugar nigerose

    J. Franceus, S. Dhaene, H. Decadt, J. Vandepitte, J. Caroen, J. Van der Eycken, K. Beerens and T. Desmet, Chem. Commun., 2019, 55, 4531
    DOI: 10.1039/C9CC01587F

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