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Issue 31, 2019
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Rational design of an improved transglucosylase for production of the rare sugar nigerose

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Abstract

The sucrose phosphorylase from Bifidobacterium adolescentis (BaSP) can be used as a transglucosylase for the production of rare sugars. We designed variants of BaSP for the efficient synthesis of nigerose from sucrose and glucose, thereby adding to the inventory of rare sugars that can conveniently be produced from bulk sugars.

Graphical abstract: Rational design of an improved transglucosylase for production of the rare sugar nigerose

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Article information


Submitted
25 Feb 2019
Accepted
26 Mar 2019
First published
26 Mar 2019

Chem. Commun., 2019,55, 4531-4533
Article type
Communication

Rational design of an improved transglucosylase for production of the rare sugar nigerose

J. Franceus, S. Dhaene, H. Decadt, J. Vandepitte, J. Caroen, J. Van der Eycken, K. Beerens and T. Desmet, Chem. Commun., 2019, 55, 4531
DOI: 10.1039/C9CC01587F

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