Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 82, 2019
Previous Article Next Article

In vivo ratiometric tracking of endogenous β-galactosidase activity using an activatable near-infrared fluorescent probe

Author affiliations

Abstract

Herein, we developed a dual-channel and light-up near-infrared fluorescent probe for ratiometric sensing of β-galactosidase (β-gal) activity. The well-designed probe, which shows ratiometric optical response with a significant red-shift (from 575 nm to 730 nm), was successfully applied to detect endogenous β-gal activity in SKOV-3 cells and tumor-bearing mice.

Graphical abstract: In vivo ratiometric tracking of endogenous β-galactosidase activity using an activatable near-infrared fluorescent probe

Back to tab navigation

Supplementary files

Article information


Submitted
03 Sep 2019
Accepted
19 Sep 2019
First published
19 Sep 2019

Chem. Commun., 2019,55, 12308-12311
Article type
Communication

In vivo ratiometric tracking of endogenous β-galactosidase activity using an activatable near-infrared fluorescent probe

L. Shi, C. Yan, Y. Ma, T. Wang, Z. Guo and W. Zhu, Chem. Commun., 2019, 55, 12308
DOI: 10.1039/C9CC06869D

Social activity

Search articles by author

Spotlight

Advertisements