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Issue 64, 2019
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Overcoming inaccessibility of fluorinated imines – synthesis of functionalized amines from readily available fluoroacetamides

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Abstract

Although imines are convenient substrates for the synthesis of functionalized amines, they may be hard to obtain, as in the case of fluorinated imines. To aid in overcoming this issue, we propose a protocol of corresponding amine synthesis from simple fluoroacetic acid-derived amides using Schwartz's reagent.

Graphical abstract: Overcoming inaccessibility of fluorinated imines – synthesis of functionalized amines from readily available fluoroacetamides

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Publication details

The article was received on 28 May 2019, accepted on 05 Jul 2019 and first published on 05 Jul 2019


Article type: Communication
DOI: 10.1039/C9CC04111G
Chem. Commun., 2019,55, 9436-9439

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    Overcoming inaccessibility of fluorinated imines – synthesis of functionalized amines from readily available fluoroacetamides

    P. J. Czerwiński and B. Furman, Chem. Commun., 2019, 55, 9436
    DOI: 10.1039/C9CC04111G

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