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Issue 47, 2019
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A NIR-triggered gatekeeper of supramolecular conjugated unimicelles with two-photon absorption for controlled drug release

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Abstract

A near-infrared (NIR)-sensitive gated assembly of supramolecular conjugated unimicelles based on robust host–guest recognition between a β-cyclodextrin-grafted hyperbranched conjugated polymer and azobenzene-functionalized poly(ethylene glycol) was constructed. Utilized as a drug carrier, these unimicelles exhibited controlled drug release through the NIR-triggered photoisomerization of azobenzene in cancer cells via a two-photon excited fluorescence resonance energy transfer (TP-FRET) approach, leading to efficient cancer therapy.

Graphical abstract: A NIR-triggered gatekeeper of supramolecular conjugated unimicelles with two-photon absorption for controlled drug release

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Publication details

The article was received on 14 Apr 2019, accepted on 07 May 2019 and first published on 07 May 2019


Article type: Communication
DOI: 10.1039/C9CC02901J
Chem. Commun., 2019,55, 6735-6738

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    A NIR-triggered gatekeeper of supramolecular conjugated unimicelles with two-photon absorption for controlled drug release

    Y. Huang, L. Shen, D. Guo, W. Yasen, Y. Wu, Y. Su, D. Chen, F. Qiu, D. Yan and X. Zhu, Chem. Commun., 2019, 55, 6735
    DOI: 10.1039/C9CC02901J

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