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Issue 50, 2019
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Crackled nanocapsules: the “imperfect” structure for enzyme immobilization

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Abstract

Herein, the first example of crackled organosilica nanocapsules (CONs) is reported to directly immobilize enzymes without any further chemical modification. Enzymes are adsorbed on both the exterior and interior surfaces of CONs, integrating the merits of adsorption and encapsulation. When used for Candida rugosa lipase (CRL) immobilization, the CONs displayed higher enzyme loading, lower enzyme leaching, and elevated enzyme activity, compared to the conventional non-crackled nanocapsules/particles.

Graphical abstract: Crackled nanocapsules: the “imperfect” structure for enzyme immobilization

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Supplementary files

Article information


Submitted
11 Apr 2019
Accepted
17 May 2019
First published
17 May 2019

Chem. Commun., 2019,55, 7155-7158
Article type
Communication

Crackled nanocapsules: the “imperfect” structure for enzyme immobilization

Q. Huo, J. Zhao, W. Li, D. Yang, S. Zhang, J. Shi and Z. Jiang, Chem. Commun., 2019, 55, 7155
DOI: 10.1039/C9CC02797A

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