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Issue 27, 2019
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A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

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Abstract

A far-red fluorescent probe has been developed for sensing fungal laccase. The probe was used to determine that Rhizopus oryzae had a high level endogenous laccase amongst 24 fungal strains. The Rhizopus oryzae was then used as a biocatalyst for the preparation of dicoumarin resulting in significant inhibition of Mycobacterium tuberculosis H37Ra.

Graphical abstract: A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

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Publication details

The article was received on 25 Feb 2019, accepted on 08 Mar 2019 and first published on 08 Mar 2019


Article type: Communication
DOI: 10.1039/C9CC01579E
Chem. Commun., 2019,55, 3951-3954
  • Open access: Creative Commons BY license
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    A far-red fluorescent probe for sensing laccase in fungi and its application in developing an effective biocatalyst for the biosynthesis of antituberculous dicoumarin

    Z. Tian, Q. Yan, L. Feng, S. Deng, C. Wang, J. Cui, C. Wang, Z. Zhang, T. D. James and X. Ma, Chem. Commun., 2019, 55, 3951
    DOI: 10.1039/C9CC01579E

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