Issue 26, 2019
From the journal:

Chemical Communications

Straightforward access to biocompatible poly(2-oxazoline)-coated nanomaterials by polymerization-induced self-assembly†

Dao Le, ORCID logo ‡ab   Friederike Wagner,‡ab   Masanari Takamiya,a   I-Lun Hsiao,ac   Gabriela Gil Alvaradejo,ab   Uwe Strähle,a   Carsten Weissa  and  Guillaume Delaittre ORCID logo *ab  

* Corresponding authors

a Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany
E-mail: guillaume.delaittre@kit.edu

b Institute for Chemical Technology and Polymer Chemistry (ITCP), Karlsruhe Institute of Technology (KIT), Engesserstr. 18, 76128 Karlsruhe, Germany

c School of Food Safety, College of Nutrition, Taipei Medical University, No. 250, Wuxing St., Taipei 11031, Taiwan

Abstract

We report the synthesis of poly(2-ethyl-2-oxazoline)-based (PEtOx) nanoobjects by polymerization-induced self-assembly (PISA). First, well-defined PEtOx macromolecular chain transfer agents were synthesized by cationic ring-opening polymerization and click chemistry. The photoinitiated PISA of 2-hydroxypropyl methacrylate mediated by these PEtOx produced nanoobjects spanning the full range of core–shell morphologies. The nanoparticles exhibited high biocompatibility and stealth properties in vitro or in vivo, as well as thermoresponsive behavior.

Graphical abstract: Straightforward access to biocompatible poly(2-oxazoline)-coated nanomaterials by polymerization-induced self-assembly

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C9CC00407F
Article type
Communication
Submitted
16 Jan 2019
Accepted
21 Feb 2019
First published
25 Feb 2019
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2019,55, 3741-3744

Permissions

Request permissions

Straightforward access to biocompatible poly(2-oxazoline)-coated nanomaterials by polymerization-induced self-assembly

D. Le, F. Wagner, M. Takamiya, I. Hsiao, G. Gil Alvaradejo, U. Strähle, C. Weiss and G. Delaittre, Chem. Commun., 2019, 55, 3741 DOI: 10.1039/C9CC00407F

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements