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Issue 12, 2019
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Quercetin dual interaction at the membrane level

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Abstract

Quercetin impact on lipid bilayers suggests a dual action mechanism at cell membranes. This widespread polyphenol displays high partition with low interference in the more fluid membrane domains, more vulnerable to oxidative attack, but strong perturbation of cholesterol/sphingolipid enriched domains, where signalling platforms are expected to assemble.

Graphical abstract: Quercetin dual interaction at the membrane level

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Article information


Submitted
04 Dec 2018
Accepted
10 Jan 2019
First published
10 Jan 2019

Chem. Commun., 2019,55, 1750-1753
Article type
Communication

Quercetin dual interaction at the membrane level

A. de Granada-Flor, C. Sousa, H. A. L. Filipe, M. S. C. S. Santos and R. F. M. de Almeida, Chem. Commun., 2019, 55, 1750
DOI: 10.1039/C8CC09656B

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