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Issue 2, 2019
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A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

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Abstract

Atomically dispersed Fe–N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.

Graphical abstract: A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

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Supplementary files

Article information


Submitted
10 Oct 2018
Accepted
19 Nov 2018
First published
19 Nov 2018

Chem. Commun., 2019,55, 159-162
Article type
Communication

A single-atom Fe–N4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection

W. Ma, J. Mao, X. Yang, C. Pan, W. Chen, M. Wang, P. Yu, L. Mao and Y. Li, Chem. Commun., 2019, 55, 159
DOI: 10.1039/C8CC08116F

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