Issue 11, 2019
From the journal:

Biomaterials Science

Photo-responsive materials with strong cell trapping ability for light-guided manipulation of nonadherent cells†

Natalia Teresa Jarzębska,a   Satoshi Yamaguchi, ORCID logo *bc   Shin Izuta,a   Takahiro Kosaka,a   Shinya Yamahira,d   Teruyuki Nagamunea  and  Akimitsu Okamoto ORCID logo *ab  

* Corresponding authors

a Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
E-mail: okamoto@chembio.t.u-tokyo.ac.jp

b Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan
E-mail: yamaguchi@bioorg.rcast.u-tokyo.ac.jp

c PRESTO, Japan Science and Technology Agency (JST), 4-1-8 Hon-cho, Kawaguchi, Saitama 351-0198, Japan

d Center for Medical Sciences, St. Luke's International University, 10-1 Akashi-Cho, Chuo-ku, Tokyo, Japan

Abstract

We report a photo-cleavable material for tight trapping of nonadherent cells to substrate surfaces. Model immunocytes were selectively trapped in a non-irradiated area as single cells after the projection of a light pattern and withstood high-speed laminar flow, achieving light-guided cell release from the substrates.

Graphical abstract: Photo-responsive materials with strong cell trapping ability for light-guided manipulation of nonadherent cells

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Article information

DOI
https://doi.org/10.1039/C9BM01200A
Article type
Communication
Submitted
30 Jul 2019
Accepted
04 Oct 2019
First published
11 Oct 2019

Biomater. Sci., 2019,7, 4514-4518

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Photo-responsive materials with strong cell trapping ability for light-guided manipulation of nonadherent cells

N. T. Jarzębska, S. Yamaguchi, S. Izuta, T. Kosaka, S. Yamahira, T. Nagamune and A. Okamoto, Biomater. Sci., 2019, 7, 4514 DOI: 10.1039/C9BM01200A

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