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Issue 11, 2019
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Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

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Abstract

The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (μg kg−1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.

Graphical abstract: Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

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Publication details

The article was received on 29 Jan 2019, accepted on 22 Mar 2019 and first published on 28 Mar 2019


Article type: Communication
DOI: 10.1039/C9AN00207C
Analyst, 2019,144, 3488-3493

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    Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

    C. Bissardon, O. Proux, S. Bureau, E. Suess, L. H. E. Winkel, R. S. Conlan, L. W. Francis, I. M. Khan, L. Charlet, J. L. Hazemann and S. Bohic, Analyst, 2019, 144, 3488
    DOI: 10.1039/C9AN00207C

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