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Issue 6, 2018
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Magnetic iron oxide nanoparticles as T1 contrast agents for magnetic resonance imaging

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Abstract

Ultrasmall iron oxide nanoparticles have recently attracted much attention as T1 (positive) contrast agents for magnetic resonance imaging to serve as safer alternatives to gadolinium-based T1 contrast agents. This review will discuss several key aspects regarding this newly developed contrast agent, including synthetic strategies, parameters affecting T1 signal (e.g., size, surface, and environment), and emerging applications. The integration with other imaging modalities will be discussed as well, such as dual T1/T2 imaging, positron emission tomography, and computed tomography. Finally, perspectives and outlook about the future development and concerns will be included.

Graphical abstract: Magnetic iron oxide nanoparticles as T1 contrast agents for magnetic resonance imaging

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Publication details

The article was received on 21 Dec 2017, accepted on 13 Jan 2018 and first published on 15 Jan 2018


Article type: Review Article
DOI: 10.1039/C7TC05854C
J. Mater. Chem. C, 2018,6, 1280-1290

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    Magnetic iron oxide nanoparticles as T1 contrast agents for magnetic resonance imaging

    Y. Bao, J. A. Sherwood and Z. Sun, J. Mater. Chem. C, 2018, 6, 1280
    DOI: 10.1039/C7TC05854C

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