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Mammalian cell: A unique scaffold for in situ biosynthesis of metallic nanomaterials and biomedical applications

Abstract

Production of nanoscale materials often requires the use of toxic chemicals and complex synthetic procedures. A new scaffold has been explored for in situ synthesis of nanomaterials that utilizes natural biological systems in the form of plants, bacteria, fungi, algae and redox-imbalanced mammalian cells and systems. The latter approach has become popular in recent years and has shown some promising results in bioimaging of cancer, as well as inflammatory and neurodegenerative maladies. Biosynthesis of nanoclusters in redox-imbalanced mammalian cells is facile, cost-effective and environmentally friendly with higher biocompatibility, target specify and lower adverse effects than traditional synthetic approaches. Herein, we describe recent advances in mammalian green in situ biosynthesis for biomedical applications, especially in cancer and neurodegenerative disease theranostics

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Publication details

The article was received on 28 Jul 2018, accepted on 06 Sep 2018 and first published on 06 Sep 2018


Article type: Review Article
DOI: 10.1039/C8TB01955J
Citation: J. Mater. Chem. B, 2018, Accepted Manuscript
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    Mammalian cell: A unique scaffold for in situ biosynthesis of metallic nanomaterials and biomedical applications

    F. U. Rehman, H. Jiang, M. Selke and X. Wang, J. Mater. Chem. B, 2018, Accepted Manuscript , DOI: 10.1039/C8TB01955J

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