Jump to main content
Jump to site search

Issue 48, 2018
Previous Article Next Article

Lipid bilayer modified gold nanorod@mesoporous silica nanoparticles for controlled drug delivery triggered by near-infrared light

Author affiliations

Abstract

Integration of various theranostic modalities into one nanoplatform for combined treatment of tumor is highly desirable in the field of biomedicine. However, it is still challenging to engineer such a platform with good biocompatibility, multifunctionality, and response to external stimuli. Herein, biocompatible lipid bilayer modified mesoporous silica coated gold nanorods (AuNRs) nanocomposites were developed. The heat from near-infrared (NIR)-stimulated AuNR cores could improve the permeability of the lipid bilayer, thereby leading to drug release. The in vitro results exhibited the DOX loaded nanocomposites to have high treatment efficiency in HeLa cells upon NIR irradiation. They may find potential in cancer treatment.

Graphical abstract: Lipid bilayer modified gold nanorod@mesoporous silica nanoparticles for controlled drug delivery triggered by near-infrared light

Back to tab navigation

Article information


Submitted
22 Jul 2018
Accepted
05 Nov 2018
First published
06 Nov 2018

J. Mater. Chem. B, 2018,6, 8078-8084
Article type
Paper

Lipid bilayer modified gold nanorod@mesoporous silica nanoparticles for controlled drug delivery triggered by near-infrared light

X. Cui, W. Cheng and X. Han, J. Mater. Chem. B, 2018, 6, 8078 DOI: 10.1039/C8TB01891J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements