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Nanoparticle-Proteome In Vitro and In Vivo


The protein corona is a concept central to a range of disciplines exploiting the bio-nano interface. As literature continues to expand in this field, it is essential to condense and contextualize the in vitro and in vivo proteome databases accumulated over the past decade: a goal which this review intends to achieve for the benefit of nanomedicine and nanobiotechnology. The parameters used for our review are the physicochemical characteristics of the nanoparticles, their surface ligands, the biological matrix from which a corona was formed, methods employed, plus the top-ten enriched corona proteins. In addition, the protein coronal networks and their implications in vivo are highlighted for selected studies.

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Publication details

The article was received on 21 Jun 2018, accepted on 30 Jul 2018 and first published on 30 Jul 2018

Article type: Review Article
DOI: 10.1039/C8TB01634H
Citation: J. Mater. Chem. B, 2018, Accepted Manuscript
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    Nanoparticle-Proteome In Vitro and In Vivo

    M. Wang, O. J. R. Gustafsson, E. H. Pilkington, A. Kakinen, I. Javed, A. Faridi, T. P. Davis and P. C. Ke, J. Mater. Chem. B, 2018, Accepted Manuscript , DOI: 10.1039/C8TB01634H

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