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NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities

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Abstract

Nitric oxide photodonor (NOD) conjugated perylene tetracarboxylate ester (TPT) based fluorescent organic TPT(NOD)4 nanoparticles (NPs) with aggregation induced NIR emission have shown photoinduced nitric oxide delivery along with a red to green emission transition. Time dependent imaging and dose dependent cytotoxicity studies of these NPs using U87MG cells demonstrate the self monitoring and real time reporting abilities and potential anticancer activity of the system, respectively.

Graphical abstract: NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities

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Publication details

The article was received on 07 May 2018, accepted on 27 Aug 2018 and first published on 29 Aug 2018


Article type: Communication
DOI: 10.1039/C8TB01209A
Citation: J. Mater. Chem. B, 2018, Advance Article
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    NIR fluorescent organic nanoparticles for photoinduced nitric oxide delivery with self monitoring and real time reporting abilities

    K. K. Behara, Y. Rajesh, A. Chaudhuri, M. Gangopadhyay, M. Mandal and N. D. Pradeep Singh, J. Mater. Chem. B, 2018, Advance Article , DOI: 10.1039/C8TB01209A

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