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Rational design of Fe3O4@C nanoparticles for simultaneous bimodal imaging and chemo-photothermal therapy in vitro and in vivo

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Abstract

We report a facile strategy to fabricate well-dispersed Fe3O4@C eccentric core–shell nanoparticles (NPs). The resulting Fe3O4@C eccentric core–shell NPs possess a high payload of doxorubicin (DOX) for use as synergetic pH/near-infrared (NIR)-sensitive drug delivery vehicles, and were applied for dual-modal magnetic resonance imaging (MRI)/photoacoustic imaging (PAI) and synergistic photothermal cancer therapy in vitro and in vivo.

Graphical abstract: Rational design of Fe3O4@C nanoparticles for simultaneous bimodal imaging and chemo-photothermal therapy in vitro and in vivo

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Publication details

The article was received on 04 May 2018, accepted on 06 Aug 2018 and first published on 11 Aug 2018


Article type: Paper
DOI: 10.1039/C8TB01184B
Citation: J. Mater. Chem. B, 2018, Advance Article
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    Rational design of Fe3O4@C nanoparticles for simultaneous bimodal imaging and chemo-photothermal therapy in vitro and in vivo

    Q. Han, X. Wang, Z. Sun, X. Xu, L. Jin, L. Qiao and Q. Yuan, J. Mater. Chem. B, 2018, Advance Article , DOI: 10.1039/C8TB01184B

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