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Issue 30, 2018
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Chemosensors for biogenic amines and biothiols

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There is burgeoning interest among supramolecular chemists to develop novel molecular systems to detect biogenic amines and bio-thiols in aqueous and non-aqueous media due to their potential role in biological processes. Biogenic amines are biologically important targets because of their involvement in the energy metabolism of human biological systems and their requirement is met through food and nutrition. However, the increasing instances of serious health problems due to food toxicity have raised the quality of food nowadays. Biogenic amines have been frequently considered as the markers or primary quality parameters of foods like antioxidant properties, freshness and spoilage. For instance, these amines such as spermine, spermidine, cadavarine, etc. may originate during microbial decarboxylation of amino acids of fermented foods/beverages. These amines may also react with nitrite available in certain meat products and concomitantly produce carcinogenic nitrosamine compounds. On the other hand, it is also well established that biothiols, particularly, thiol amino acids, provide the basic characteristics to food including flavor, color and texture that determine its acceptability. For instance, the reduction of thiol groups produces hydrogen sulfide which reduces flavour as in rotten eggs and spoiled fish, and the presence of hydrogen sulfide in fish is indicative of spoilage. Thus, biogenic amines and bio-thiols have attracted the profound interest of researchers as analytical tools for their quantification. Much scientific and technological information is issued every year, where the establishment of precise interactions of biogenic amines and bio-thiols with other molecules is sought in aqueous and non-aqueous media. This review summarizes the optical chemosensors developed for the selective detection of biogenic amines and bio-thiols.

Graphical abstract: Chemosensors for biogenic amines and biothiols

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Publication details

The article was received on 17 Mar 2018, accepted on 20 Jun 2018 and first published on 22 Jun 2018

Article type: Review Article
DOI: 10.1039/C8TB00732B
Citation: J. Mater. Chem. B, 2018,6, 4872-4902

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    Chemosensors for biogenic amines and biothiols

    N. Kaur, S. Chopra, G. Singh, P. Raj, A. Bhasin, S. K. Sahoo, A. Kuwar and N. Singh, J. Mater. Chem. B, 2018, 6, 4872
    DOI: 10.1039/C8TB00732B

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