Jump to main content
Jump to site search

Issue 17, 2018
Previous Article Next Article

Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging

Author affiliations

Abstract

Fluorescent organic nanoparticles based on small molecules have emerged as an attractive class of fluorescent agents for bioimaging in recent years. Herein, we report orange light-emitting BTPEBD based organic nanoparticles (BTPEBD NPs) with a large Stokes shift (>135 nm), ultrahigh quantum yield (>90% in water) and aggregation-induced emission characteristics. Single nanoparticle analysis studied by wide field microscopy imaging further proves that the BTPEBD NPs exhibit high brightness and good photostability. Both in vitro and in vivo experiments reveal that the BTPEBD NPs are promising fluorescent agents for cellular imaging and real-time two-photon lung vasculature imaging.

Graphical abstract: Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging

Back to tab navigation

Article information


Submitted
08 Feb 2018
Accepted
03 Apr 2018
First published
11 Apr 2018

J. Mater. Chem. B, 2018,6, 2630-2636
Article type
Paper

Organic nanoparticles with ultrahigh quantum yield and aggregation-induced emission characteristics for cellular imaging and real-time two-photon lung vasculature imaging

J. Liu, M. Evrard, X. Cai, G. Feng, N. Tomczak, L. G. Ng and B. Liu, J. Mater. Chem. B, 2018, 6, 2630
DOI: 10.1039/C8TB00386F

Social activity

Search articles by author

Spotlight

Advertisements