Jump to main content
Jump to site search
SCHEDULED MAINTENANCE Close the message box

Maintenance work is planned for Monday 16 August 2021 from 07:00 to 23:59 (BST).

Website performance may be temporarily affected and you may not be able to access some PDFs or images. If this does happen, refreshing your web browser should resolve the issue. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 14, 2018

Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy

Author affiliations

Abstract

Two dimensional (2D) semiconducting nanomaterials have shown great potential for antitumor therapy. However, their clinical applications are seriously hampered by the tumour microenvironments. Bearing this in mind, we propose to improve the performance of 2D semiconducting nanomaterials using artificial catalase. In this work, we decorate black phosphorus (BP) nanosheets with Pt nanoparticles (NPs) through an in situ growth strategy. Pt NPs as artificial catalases can efficiently decompose the accumulated H2O2 in tumours to relieve tumour hypoxia, and thereafter improve the photodynamic antitumor activity of BP nanosheets. This work paves a new avenue for the functionalization of 2D semiconducting nanomaterials, which will promote the development of 2D semiconductor based nanodrugs.

Graphical abstract: Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy

Supplementary files

Article information


Submitted
06 Feb 2018
Accepted
07 Mar 2018
First published
09 Mar 2018

J. Mater. Chem. B, 2018,6, 2057-2064
Article type
Paper

Marriage of artificial catalase and black phosphorus nanosheets for reinforced photodynamic antitumor therapy

J. Ouyang, Y. Deng, W. Chen, Q. Xu, L. Wang, Z. Liu, F. Tang, L. Deng and Y. Liu, J. Mater. Chem. B, 2018, 6, 2057 DOI: 10.1039/C8TB00371H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements