Jump to main content
Jump to site search


Laser Trapping/confocal Raman Spectroscopic Characterization of PLGA-PEG Nanoparticles

Abstract

We have immobilized poly(ethylene glycol) (PEG) on surface of poly(lactic-co-glycolic acid) (PLGA) nanoparticles by two different chemical methods, i.e., SOCl2 halogennate-alcoholysis and DCC dehydration. The immobilized PLGA nanoparticles were characterized by DLS, 1H NMR, FT-IR and laser trapping/confocal Raman spectroscopic technique. As a result, especially the Raman spectra which were measured after optically trapping less than ten individual nanoparticles in solution, indicated that the PLGA nanoparticles were successfully immobilized with the PEG by the chemical method.

Back to tab navigation

Supplementary files

Publication details

The article was received on 04 Jul 2018, accepted on 12 Sep 2018 and first published on 13 Sep 2018


Article type: Communication
DOI: 10.1039/C8SM01364K
Citation: Soft Matter, 2018, Accepted Manuscript
  •   Request permissions

    Laser Trapping/confocal Raman Spectroscopic Characterization of PLGA-PEG Nanoparticles

    J. Yang, R. Zhang, D. Liu, X. Zhou, T. Shoji, Y. Tsuboi and H. Yan, Soft Matter, 2018, Accepted Manuscript , DOI: 10.1039/C8SM01364K

Search articles by author

Spotlight

Advertisements