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Issue 8, 2018
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Methylene violet 3RAX-conjugated porphyrin for photodynamic therapy: synthesis, DNA photocleavage, and cell study

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Abstract

A methylene violet 3RAX-conjugated porphyrin has been designed and synthesized as a potential photosensitizer in photodynamic therapy because of its high DNA binding constant and the efficacy in inhibiting cancer cells with subcellular localization.

Graphical abstract: Methylene violet 3RAX-conjugated porphyrin for photodynamic therapy: synthesis, DNA photocleavage, and cell study

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Supplementary files

Article information


Submitted
09 Dec 2017
Accepted
16 Jan 2018
First published
24 Jan 2018

This article is Open Access

RSC Adv., 2018,8, 4472-4477
Article type
Paper

Methylene violet 3RAX-conjugated porphyrin for photodynamic therapy: synthesis, DNA photocleavage, and cell study

S. Yao, Y. Zheng, L. Jiang, C. Xie, F. Wu, C. Huang, X. Zhang, K. Wong, Z. Li and K. Wang, RSC Adv., 2018, 8, 4472
DOI: 10.1039/C7RA13176C

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    [Original citation] - Published by The Royal Society of Chemistry.

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