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Ru(II)-Catalyzed C6-selective C–H amidation of 2-pyridones

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Abstract

Ru(II)-Catalyzed C6 site-selective amidation of 2-pyridones with 1,4,2-dioxazol-5-ones has been developed. The reaction occurred with a low catalyst loading and broad substrate scope under mild conditions, affording desired products in up to 98% yields within a short time.

Graphical abstract: Ru(ii)-Catalyzed C6-selective C–H amidation of 2-pyridones

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Publication details

The article was received on 30 Jul 2018, accepted on 12 Sep 2018 and first published on 13 Sep 2018


Article type: Research Article
DOI: 10.1039/C8QO00795K
Citation: Org. Chem. Front., 2018, Advance Article
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    Ru(II)-Catalyzed C6-selective C–H amidation of 2-pyridones

    L. Zhang, X. Zheng, J. Chen, K. Cheng, L. Jin, X. Jiang and C. Yu, Org. Chem. Front., 2018, Advance Article , DOI: 10.1039/C8QO00795K

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