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Issue 17, 2018
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Bromide-catalyzed electrochemical trifluoromethylation/cyclization of N-arylacrylamides with low catalyst loading

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Abstract

The electrochemical trifluoromethylarylation of N-arylacrylamides catalyzed by bromide is described. The synthetic utility of this methodology is demonstrated by transition metal-free and external oxidant-free conditions, and low catalyst loading.

Graphical abstract: Bromide-catalyzed electrochemical trifluoromethylation/cyclization of N-arylacrylamides with low catalyst loading

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Publication details

The article was received on 30 Jun 2018, accepted on 27 Jul 2018 and first published on 30 Jul 2018


Article type: Research Article
DOI: 10.1039/C8QO00645H
Org. Chem. Front., 2018,5, 2573-2577

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    Bromide-catalyzed electrochemical trifluoromethylation/cyclization of N-arylacrylamides with low catalyst loading

    Y. Jiang, G. Dou, K. Xu and C. Zeng, Org. Chem. Front., 2018, 5, 2573
    DOI: 10.1039/C8QO00645H

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