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Issue 8, 2018
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Metal-free intermolecular aminochlorination of unactivated alkenes

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Abstract

We report a metal-free method for the synthesis of vicinal chloroamines by intermolecular aminochlorination of unactivated alkenes. This regioselective reaction is inexpensive, atom economical, and environmentally benign and tolerates various functional groups. The aminochlorinated product can be easily deprotected and subsequently transformed into valuable compounds.

Graphical abstract: Metal-free intermolecular aminochlorination of unactivated alkenes

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Article information


Submitted
02 Jan 2018
Accepted
09 Feb 2018
First published
09 Feb 2018

Org. Chem. Front., 2018,5, 1303-1307
Article type
Research Article

Metal-free intermolecular aminochlorination of unactivated alkenes

N. Zhu, Y. Li and H. Bao, Org. Chem. Front., 2018, 5, 1303
DOI: 10.1039/C8QO00001H

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