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Issue 4, 2018
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Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

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Abstract

A cobalt-catalyzed cross-dehydrogenative coupling of 2-arylimidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant is reported. A broad range of 2-arylimidazo[1,2-a]pyridines reacted smoothly to afford the corresponding products in moderate to good yields. The advantages of this method are: inexpensive catalysts, environmentally benign conditions and operational convenience.

Graphical abstract: Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

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Article information


Submitted
26 Sep 2017
Accepted
24 Oct 2017
First published
26 Oct 2017

Org. Chem. Front., 2018,5, 577-581
Article type
Research Article

Cobalt-catalyzed cross-dehydrogenative coupling of imidazo[1,2-a]pyridines with isochroman using molecular oxygen as the oxidant

Q. Yang, S. Li and J. (. Wang, Org. Chem. Front., 2018, 5, 577
DOI: 10.1039/C7QO00875A

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