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Issue 3, 2018
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Pyridinium salts: from synthesis to reactivity and applications

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Structurally diverse pyridinium salts are quite familiar structures in many natural products and bioactive pharmaceuticals. Over the centuries, these privileged scaffolds have played an intriguing role in a wide range of research topics and, thus, this review aims at highlighting the pyridinium salts in terms of their synthetic routes, reactivity and their importance as pyridinium ionic liquids, as pyridinium ylides, as anti-microbial, anti-cancer, anti-malarial and anti-cholinesterase inhibitors, as well as their applications in materials science and biological issues related to gene delivery.

Graphical abstract: Pyridinium salts: from synthesis to reactivity and applications

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The article was received on 15 Sep 2017, accepted on 25 Oct 2017 and first published on 03 Nov 2017

Article type: Review Article
DOI: 10.1039/C7QO00836H
Citation: Org. Chem. Front., 2018,5, 453-493

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    Pyridinium salts: from synthesis to reactivity and applications

    S. Sowmiah, J. M. S. S. Esperança, L. P. N. Rebelo and C. A. M. Afonso, Org. Chem. Front., 2018, 5, 453
    DOI: 10.1039/C7QO00836H

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