Jump to main content
Jump to site search

Issue 5, 2018
Previous Article Next Article

Photoredox 1,2-dicarbofunctionalization of unactivated alkenes via tandem radical difluoroalkylation and alkynyl migration

Author affiliations

Abstract

Visible-light-mediated tandem radical difluoroalkylation and alkynylation of unactivated alkenes is described in this communication. The process comprises a mild C–C bond activation via intramolecular 1,4-alkynyl migration. The general and elegant protocol can serve as a straightforward access route to obtain a wide range of synthetically valuable difluoroalkylated linear alkynyl ketones under mild reaction conditions.

Graphical abstract: Photoredox 1,2-dicarbofunctionalization of unactivated alkenes via tandem radical difluoroalkylation and alkynyl migration

Back to tab navigation

Supplementary files

Article information


Submitted
07 Sep 2017
Accepted
03 Nov 2017
First published
06 Nov 2017

Org. Chem. Front., 2018,5, 797-800
Article type
Research Article

Photoredox 1,2-dicarbofunctionalization of unactivated alkenes via tandem radical difluoroalkylation and alkynyl migration

J. Liu, W. Li, J. Xie and C. Zhu, Org. Chem. Front., 2018, 5, 797
DOI: 10.1039/C7QO00808B

Social activity

Search articles by author

Spotlight

Advertisements