Jump to main content
Jump to site search

Issue 40, 2018
Previous Article Next Article

An efficient strategy for achieving controlled ring-opening polymerization of O-carboxyanhydrides via amine initiation in collaboration with metal-alkoxide catalysis

Author affiliations

Abstract

The ring-opening polymerization (ROP) of O-carboxyanhydrides (OCAs) is a versatile alternative for generating well-defined functional poly(α-hydroxy acids) (PAHAs). In contrast to the ROP of lactides, which has countless successful examples, exploring new catalysts and polymerization pathways for the controlled ROP of OCAs remains an attractive challenge. Considering the polymerization characteristics of OCAs, we herein describe an effective catalytic system containing Zn(C6F5)2 and amines that mediates the controlled ROP of OCAs. The strong nucleophilic attack of the amines combined with the effective switching of Zn(C6F5)2 to Zn alkoxide during polymerization provides a collaborative catalytic pathway of amine initiation and metal-alkoxide-promoted chain propagation for the ROP of OCAs. The ROP of OCAs catalyzed by Zn(C6F5)2 and amines enables the controlled polymerization of PAHA, as evidenced by the afforded homopolymers and block polymers with the expected molecular weights and narrow molecular weight distributions (Mw/Mn < 1.1). Careful analysis of the polymerization system and computational studies verify a Lewis pair composed of amines and Zn(C6F5)2 for polymerization initiation and functionality switch from Zn(C6F5)2 to a metal-alkoxide species for coordination–insertion chain propagation.

Graphical abstract: An efficient strategy for achieving controlled ring-opening polymerization of O-carboxyanhydrides via amine initiation in collaboration with metal-alkoxide catalysis

Back to tab navigation

Supplementary files

Publication details

The article was received on 24 Jul 2018, accepted on 12 Sep 2018 and first published on 15 Sep 2018


Article type: Paper
DOI: 10.1039/C8PY01090K
Citation: Polym. Chem., 2018,9, 5014-5023
  •   Request permissions

    An efficient strategy for achieving controlled ring-opening polymerization of O-carboxyanhydrides via amine initiation in collaboration with metal-alkoxide catalysis

    Y. Nie, P. Wang, H. Du, W. Meng and J. Yang, Polym. Chem., 2018, 9, 5014
    DOI: 10.1039/C8PY01090K

Search articles by author

Spotlight

Advertisements