Jump to main content
Jump to site search

Issue 20, 2018
Previous Article Next Article

The secondary structures of PEG-functionalized random copolymers derived from (R)- and (S)- families of alkyne polycarbodiimides

Author affiliations

Abstract

A series of helical rigid-rod (R)- and (S)-polycarbodiimides having PEG2K, 10K, and 20K groups attached to aromatic or aliphatic side chains have been successfully synthesized from the respective alkyne polycarbodiimide precursors using the CuI-catalyzed azide/alkyne cycloaddition (CuAAC) reaction. The AFM, TEM and SEM studies of this series revealed the formation of different types of aggregated morphologies, i.e., micro- and nanospheres, fiber-like crystallites, and porous aggregates, which can be tailored with the hydrophilic PEG segments in the polymer structure. In general, heavily PEGylated scaffolds comprising ∼44 ethylene oxide segments are prone to form round-shaped secondary structures, especially in the bulk, as evident by SEM measurements. AFM data suggested that spherical aggregates are the preferred motifs in a wide range of concentrations. Moreover, polycarbodiimide-graft-PEG(2K) random copolymers were shown to efficiently suspend SWCNTs in water, leading to novel neutral photoluminescent nanocomposite materials. Overall, these extensive self-assembly studies on various polycarbodiimide platforms featuring a hydrophobic rigid rod main chain and a flexible hydrophilic periphery may provide a basic layout for prospective biomedical applications, such as controlled drug delivery and enhanced dispersibility properties of SWCNTs.

Graphical abstract: The secondary structures of PEG-functionalized random copolymers derived from (R)- and (S)- families of alkyne polycarbodiimides

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Feb 2018, accepted on 27 Apr 2018 and first published on 10 May 2018


Article type: Paper
DOI: 10.1039/C8PY00282G
Polym. Chem., 2018,9, 2759-2768

  •   Request permissions

    The secondary structures of PEG-functionalized random copolymers derived from (R)- and (S)- families of alkyne polycarbodiimides

    O. V. Kulikov, D. A. Siriwardane, J. Budhathoki-Uprety, G. T. McCandless, S. F. Mahmood and B. M. Novak, Polym. Chem., 2018, 9, 2759
    DOI: 10.1039/C8PY00282G

Search articles by author

Spotlight

Advertisements