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Issue 7, 2018
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Palladium-polymer nanoreactors for the aqueous asymmetric synthesis of therapeutic flavonoids

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Abstract

Polymeric core–shell micelles incorporating a chiral palladium pyridinooxazoline catalyst are presented as nanoreactors for the aqueous asymmetric synthesis of flavanones, a class of flavonoids with therapeutic properties. Use of the nanoreactor was found to increase catalyst activity, enabling catalysis at room temperature, with low palladium loadings and without any additives.

Graphical abstract: Palladium-polymer nanoreactors for the aqueous asymmetric synthesis of therapeutic flavonoids

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Article information


Submitted
07 Dec 2017
Accepted
18 Jan 2018
First published
30 Jan 2018

Polym. Chem., 2018,9, 820-823
Article type
Communication

Palladium-polymer nanoreactors for the aqueous asymmetric synthesis of therapeutic flavonoids

E. Lestini, L. D. Blackman, C. M. Zammit, T. Chen, R. J. Williams, M. Inam, B. Couturaud and R. K. O'Reilly, Polym. Chem., 2018, 9, 820
DOI: 10.1039/C7PY02050C

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