Issue 1, 2019

Photoantimicrobials and PACT: what's in an abbreviation?

Abstract

The use of a separate nomenclature for the application of photosensitisers to the oncological and infectious disease fields represents a sensible approach. There is commonality, of course, in that both utilise light activation and act via the local generation of reactive oxygen species, but the difference in cellular targets is so great that different designs are required to achieve proper selectivity for a clinical end use, whether in human or veterinary medicine. The following represents a personal view, and perhaps a clarification of terms, in what might be considered a major etymological dichotomy existing within photodynamic research, on the 20th anniversary of “PACT”.

Graphical abstract: Photoantimicrobials and PACT: what's in an abbreviation?

Article information

Article type
Forum
Submitted
03 Sep 2018
Accepted
16 Oct 2018
First published
19 Oct 2018

Photochem. Photobiol. Sci., 2019,18, 12-14

Photoantimicrobials and PACT: what's in an abbreviation?

M. Wainwright, Photochem. Photobiol. Sci., 2019, 18, 12 DOI: 10.1039/C8PP00390D

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