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Issue 7, 2019
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Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

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Abstract

Fluoroalkylated alkynes, which are versatile building blocks for the synthesis of various biologically active organofluorine compounds, were synthesized from easily available alkynyl halides and fluoroalkyl halides by visible-light photocatalysis. Addition of fluoroalkyl radicals to alkynes and subsequent dehalogenation selectively yielded fluoroalkylated alkynes.

Graphical abstract: Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

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Article information


Submitted
06 Oct 2018
Accepted
06 Nov 2018
First published
07 Nov 2018

Org. Biomol. Chem., 2019,17, 1758-1762
Article type
Communication

Synthesis of fluoroalkylated alkynes via visible-light photocatalysis

N. Iqbal, N. Iqbal, S. S. Han and E. J. Cho, Org. Biomol. Chem., 2019, 17, 1758
DOI: 10.1039/C8OB02486C

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