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Electrochemical cobalt-catalyzed C–H or N–H oxidation: a facile route to synthesis of substituted oxindoles

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Abstract

Two comparable protocols for the electrochemical cobalt-catalyzed C–H/N–H oxidation have been exploited for the synthesis of substituted oxindoles via radical pathways. The electrochemical cobalt-catalyzed system was demonstrated to be efficient and eco-friendly and avoided the use of stoichiometric oxidants to afford the arylation or alkylation products in good yields at room temperature.

Graphical abstract: Electrochemical cobalt-catalyzed C–H or N–H oxidation: a facile route to synthesis of substituted oxindoles

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Publication details

The article was received on 06 Oct 2018, accepted on 01 Nov 2018 and first published on 01 Nov 2018


Article type: Communication
DOI: 10.1039/C8OB02485E
Citation: Org. Biomol. Chem., 2018, Advance Article
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    Electrochemical cobalt-catalyzed C–H or N–H oxidation: a facile route to synthesis of substituted oxindoles

    Y. Yu, P. Zheng, Y. Wu and X. Ye, Org. Biomol. Chem., 2018, Advance Article , DOI: 10.1039/C8OB02485E

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