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Issue 2, 2019
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An enantioselective assembly of naphthopyran via NHC-catalyzed [3 + 3] annulation of bromoenal with β-tetralone

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Abstract

An asymmetric assembly of naphthopyran was realized via the N-heterocyclic carbene (NHC)-catalyzed formal [3 + 3] annulation of bromoenal and β-tetralone. The key advantages of this protocol include ready availability of starting materials, mild reaction conditions, good yields and excellent enantioselectivities.

Graphical abstract: An enantioselective assembly of naphthopyran via NHC-catalyzed [3 + 3] annulation of bromoenal with β-tetralone

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Publication details

The article was received on 05 Sep 2018, accepted on 04 Dec 2018 and first published on 05 Dec 2018


Article type: Paper
DOI: 10.1039/C8OB02192A
Citation: Org. Biomol. Chem., 2019,17, 268-274

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    An enantioselective assembly of naphthopyran via NHC-catalyzed [3 + 3] annulation of bromoenal with β-tetralone

    S. Li, Y. Yao, Z. Tang, B. Sun, C. Yu, T. Li and C. Yao, Org. Biomol. Chem., 2019, 17, 268
    DOI: 10.1039/C8OB02192A

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