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Issue 1, 2019
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Non-toxic cyanide sources and cyanating agents

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Abstract

The present review gives an overview over non-toxic cyanation agents and cyanide sources used in the synthesis of structurally diverse products containing the nitrile function. Nucleophilic as well as electrophilic agents/systems that transfer the entire CN-group were taken in consideration. Reactions in which a preexisting carbon functionality is transformed into a nitrile function by addition of nitrogen are however not covered here.

Graphical abstract: Non-toxic cyanide sources and cyanating agents

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Article information


Submitted
30 Aug 2018
Accepted
25 Sep 2018
First published
25 Sep 2018

Org. Biomol. Chem., 2019,17, 11-23
Article type
Review Article

Non-toxic cyanide sources and cyanating agents

A. M. Nauth and T. Opatz, Org. Biomol. Chem., 2019, 17, 11
DOI: 10.1039/C8OB02140F

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