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Issue 38, 2018
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Metal- and base-free synthesis of functionalized α,α-difluoroimines via electrophilic fluorination of N-substituted enamines

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Abstract

A metal- and base-free synthesis of functionalized α,α-difluoroimines is presented. The reaction features mild conditions, high E/Z control and broad functional group tolerance. The utility of the products was demonstrated through valuable synthetic transformations.

Graphical abstract: Metal- and base-free synthesis of functionalized α,α-difluoroimines via electrophilic fluorination of N-substituted enamines

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Publication details

The article was received on 08 Aug 2018, accepted on 12 Sep 2018 and first published on 13 Sep 2018


Article type: Communication
DOI: 10.1039/C8OB01941J
Citation: Org. Biomol. Chem., 2018,16, 6895-6899
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    Metal- and base-free synthesis of functionalized α,α-difluoroimines via electrophilic fluorination of N-substituted enamines

    F. Li, C. Qiu, G. Yin, C. Wang and Z. Li, Org. Biomol. Chem., 2018, 16, 6895
    DOI: 10.1039/C8OB01941J

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