Jump to main content
Jump to site search


Glycodendron–rhenium complexes as luminescent probes for lectin sensing

Author affiliations

Abstract

The design, synthesis and characterization of novel glycoconjugate luminescent probes based on dinuclear rhenium(I) complexes are reported. A multivalent platform bearing different carbohydrate moieties (Glc, Gal and Man) was used to target carbohydrate-binding proteins (lectins), exploiting the unique photophysical characteristics of a Re(I) luminophore for protein sensing. Our results show that these glycoconjugates, non-luminescent in aqueous medium, are able to specifically bind different lectins (ConA and PNA) with a consequent enhancement of emission intensity. These findings suggest the use of Re(I)-based glycoconjugates as switch-on luminescent probe tools in biological applications.

Graphical abstract: Glycodendron–rhenium complexes as luminescent probes for lectin sensing

Back to tab navigation

Supplementary files

Publication details

The article was received on 30 Jul 2018, accepted on 05 Sep 2018 and first published on 05 Sep 2018


Article type: Paper
DOI: 10.1039/C8OB01838C
Citation: Org. Biomol. Chem., 2018, Advance Article
  •   Request permissions

    Glycodendron–rhenium complexes as luminescent probes for lectin sensing

    A. Palmioli, M. Panigati and A. Bernardi, Org. Biomol. Chem., 2018, Advance Article , DOI: 10.1039/C8OB01838C

Search articles by author

Spotlight

Advertisements