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A fast-response and highly specific Si-Rhodamine probe for endogenous peroxynitrite detection in living cells

Abstract

Peroxynitrite (ONOO−) is involved in a variety of physiological and pathological processes. We designed and synthesized the fluorescent probe SiNH based on Si-rhodamine. The nanoprobe SiNH encapsulated within the amphiphilic copolymer performs fast-response within 10 s and highlg specific for ONOO− in aqueous solution. It is demonstrated that the nanoprobe SiNH is applicable to real-time trace endogenous ONOO− in living cells.

  • This article is part of the themed collection: New Talent
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Publication details

The article was received on 06 Jul 2018, accepted on 30 Jul 2018 and first published on 30 Jul 2018


Article type: Paper
DOI: 10.1039/C8OB01598H
Citation: Org. Biomol. Chem., 2018, Accepted Manuscript
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    A fast-response and highly specific Si-Rhodamine probe for endogenous peroxynitrite detection in living cells

    J. Tang, Q. Li, Z. Guo and W. Zhu, Org. Biomol. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8OB01598H

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