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Issue 33, 2018
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Ruthenium-catalyzed synthesis of arylethyl 1,3,5-triazines from arylallyl alcohols and biguanides

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Abstract

An efficient ruthenium-catalyzed synthesis of alkyl-1,3,5-triazies from arylallyl alcohols and biguanides has been developed. The reaction occurred in moderate to good yields and tolerated heterocyclic or aryl allyl alcohols containing functionalities such as alkanes, ethers, and halogens. The reaction proceeds through a one-pot sequence of transfer hydrogenation and condensation steps.

Graphical abstract: Ruthenium-catalyzed synthesis of arylethyl 1,3,5-triazines from arylallyl alcohols and biguanides

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Publication details

The article was received on 13 Jun 2018, accepted on 06 Aug 2018 and first published on 07 Aug 2018


Article type: Paper
DOI: 10.1039/C8OB01397G
Citation: Org. Biomol. Chem., 2018,16, 6140-6145

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    Ruthenium-catalyzed synthesis of arylethyl 1,3,5-triazines from arylallyl alcohols and biguanides

    M. Zeng, Z. P. Xie, D. Cui and C. Zhang, Org. Biomol. Chem., 2018, 16, 6140
    DOI: 10.1039/C8OB01397G

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