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Issue 14, 2018
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Visualization of mercury(ii) accumulation in vivo using bioluminescence imaging with a highly selective probe

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Abstract

Mercury is a highly toxic environmental pollutant that negatively affects human health. Thus, an in vivo method for noninvasive imaging of mercury(II) and visualization of its accumulation within living systems would be advantageous. Herein, we describe a reaction-based bioluminescent probe for detection of mercury(II) in vitro and accumulation in vivo. The application of this probe would help to shed light on the intricate contributions of mercury(II) to various physiological and pathological processes.

Graphical abstract: Visualization of mercury(ii) accumulation in vivo using bioluminescence imaging with a highly selective probe

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Supplementary files

Article information


Submitted
14 Feb 2018
Accepted
13 Mar 2018
First published
13 Mar 2018

Org. Biomol. Chem., 2018,16, 2388-2392
Article type
Communication

Visualization of mercury(II) accumulation in vivo using bioluminescence imaging with a highly selective probe

B. Ke, H. Chen, L. Ma, S. Zingales, D. Gong, D. Hu, L. Du and M. Li, Org. Biomol. Chem., 2018, 16, 2388
DOI: 10.1039/C8OB00398J

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