Perali Ramu Sridhar, B. C. Venkatesh, Shaik Kalesha and Chalapala Sudharani
Org. Biomol. Chem., 2018,16, 3732-3740
DOI:
10.1039/C8OB00263K,
Paper
The first total synthesis of a structurally diverse mixed ligand siderophore, gobichelin B produced by Streptomyces sp. NRRL F-4415, is reported. The systematic assembly of the building blocks to synthesize Gob-B 1st half and Gob-B 2nd half and subsequent coupling of these two fragments followed by global deprotection using Pearlman's catalyst led to the isolation of gobichelin B in excellent yield and purity.
