Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes

Christopher M. Dias; Hongyu Li; Hennie Valkenier; Louise E. Karagiannidis; Philip A. Gale; David N. Sheppard; Anthony P. Davis

doi:10.1039/C7OB02787G

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Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes†

Christopher M. Dias,

^a Hongyu Li,

^b Hennie Valkenier,

^c Louise E. Karagiannidis,^d Philip A. Gale,

*^e David N. Sheppard

^b and Anthony P. Davis

*^a

Author affiliations

* Corresponding authors

^a School of Chemistry, University of Bristol, Cantock's Close, Bristol, UK
E-mail: anthony.davis@bristol.ac.uk

^b School of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol, UK

^c Engineering of Molecular NanoSystems, Ecole Polytechnique de Bruxelles, Université Libre de Bruxelles, Avenue F.D. Roosevelt 50, CP165/64, B-1050 Brussels, Belgium

^d Chemistry, University of Southampton, Southampton, UK

^e School of Chemistry, The University of Sydney, NSW 2006, Australia
E-mail: philip.gale@sydney.edu.au

Abstract

Ortho-Phenylene bis-ureas serve as anionophores in cells expressing halide-sensitive yellow fluorescent protein, as well as in synthetic vesicles. Activities can reach high levels, and are strongly dependent on the deliverability of the transporters.

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Article information

DOI: https://doi.org/10.1039/C7OB02787G
Article type: Communication
Submitted: 14 Nov 2017
Accepted: 30 Nov 2017
First published: 29 Jan 2018
This article is Open Access

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Org. Biomol. Chem., 2018,16, 1083-1087

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Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes

C. M. Dias, H. Li, H. Valkenier, L. E. Karagiannidis, P. A. Gale, D. N. Sheppard and A. P. Davis, Org. Biomol. Chem., 2018, 16, 1083 DOI: 10.1039/C7OB02787G

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Organic & Biomolecular Chemistry

Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes†

Abstract

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Anion transport by ortho-phenylene bis-ureas across cell and vesicle membranes

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