Issue 45, 2018
From the journal:

Nanoscale

Dy-DOTA integrated mesoporous silica nanoparticles as promising ultrahigh field magnetic resonance imaging contrast agents†

Xiao-Yu Zheng,a   Juan Pellico, ORCID logo a   Alexandr A. Khrapitchev, ORCID logo b   Nicola R. Sibson ORCID logo b  and  Jason J. Davis ORCID logo *a  

* Corresponding authors

a Department of Chemistry, University of Oxford, South Parks Road, Oxford, UK
E-mail: jason.davis@chem.ox.ac.uk
Fax: +44 (0)1865272 690
Tel: +44 (0)1865 275 914

b Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, UK

Abstract

Integrating Dy-DOTA motifs into mesoporous silica nanoparticle scaffolds generates remarkable ultrahigh field T2 relaxivities for a well-defined and tailorable contrast agent, attributed to enhanced Curie outer-sphere contributions as supported by simulation.

Graphical abstract: Dy-DOTA integrated mesoporous silica nanoparticles as promising ultrahigh field magnetic resonance imaging contrast agents

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Article information

DOI
https://doi.org/10.1039/C8NR07198E
Article type
Communication
Submitted
13 Sep 2018
Accepted
08 Nov 2018
First published
08 Nov 2018

Nanoscale, 2018,10, 21041-21045

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Dy-DOTA integrated mesoporous silica nanoparticles as promising ultrahigh field magnetic resonance imaging contrast agents

X. Zheng, J. Pellico, A. A. Khrapitchev, N. R. Sibson and J. J. Davis, Nanoscale, 2018, 10, 21041 DOI: 10.1039/C8NR07198E

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