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Issue 11, 2018
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Rapid fabrication of solid-state nanopores with high reproducibility over a large area using a helium ion microscope

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Abstract

The fabrication of solid-state nanopores in an insulating membrane has attracted much attention for biomolecule analysis such as DNA sequencing and detection in recent years. For practical applications and device integration, the challenges include precise size control for sub 10 nm nanopores, excellent repeatability and rapid fabrication over a large area to reduce the cost for mass production. A helium ion beam could provide an effective fabrication approach to produce such solid-state nanopores. It is easy to control the nanopore size and reach sub 10 nm pore size with a simple change in the milling time with an appropriate ion beam current. Here we report new results in a set of experiments demonstrating that with a small range of stage automatized motions and equal mill times one can obtain good fabrication reproducibility in nanopore sizes (<10% variation in size). The automation in the stage motion and milling time opens a door for the rapid mass production of nanopore chips over a wafer size of several inches.

Graphical abstract: Rapid fabrication of solid-state nanopores with high reproducibility over a large area using a helium ion microscope

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Article information


Submitted
11 Nov 2017
Accepted
29 Jan 2018
First published
30 Jan 2018

Nanoscale, 2018,10, 5198-5204
Article type
Paper

Rapid fabrication of solid-state nanopores with high reproducibility over a large area using a helium ion microscope

D. Xia, C. Huynh, S. McVey, A. Kobler, L. Stern, Z. Yuan and X. S. Ling, Nanoscale, 2018, 10, 5198
DOI: 10.1039/C7NR08406D

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