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Issue 10, 2018
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Programmable DNA switches and their applications

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DNA switches are ideally suited for numerous nanotechnological applications, and increasing efforts are being directed toward their engineering. In this review, we discuss how to engineer these switches starting from the selection of a specific DNA-based recognition element, to its adaptation and optimisation into a switch, with applications ranging from sensing to drug delivery, smart materials, molecular transporters, logic gates and others. We provide many examples showcasing their high programmability and recent advances towards their real life applications. We conclude with a short perspective on this exciting emerging field.

Graphical abstract: Programmable DNA switches and their applications

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Publication details

The article was received on 02 Oct 2017, accepted on 08 Feb 2018 and first published on 12 Feb 2018

Article type: Review Article
DOI: 10.1039/C7NR07348H
Citation: Nanoscale, 2018,10, 4607-4641
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    Programmable DNA switches and their applications

    S. G. Harroun, C. Prévost-Tremblay, D. Lauzon, A. Desrosiers, X. Wang, L. Pedro and A. Vallée-Bélisle, Nanoscale, 2018, 10, 4607
    DOI: 10.1039/C7NR07348H

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