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The Knoevenagel condensation using quinine as organocatalyst under solvent-free condition

Abstract

The Knoevenagel condensation between active methylene compounds and aromatic carobonyl compounds has been developed using quinine as organocatalyst to afford various electrophilic alkenes in excellent yields (up to 90%). In the presence of catalytic amount quinine (15 mol%) the reaction proceeded at room temperature under solvent-free conditions. In this green approach, the organocatalyst was recovered and recycled up to four cycles without appreciable loss of activity.

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Publication details

The article was received on 17 Aug 2018, accepted on 06 Nov 2018 and first published on 09 Nov 2018


Article type: Paper
DOI: 10.1039/C8NJ04219E
Citation: New J. Chem., 2018, Accepted Manuscript
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    The Knoevenagel condensation using quinine as organocatalyst under solvent-free condition

    K. Jain, S. Chaudhuri, K. Pal and K. Das, New J. Chem., 2018, Accepted Manuscript , DOI: 10.1039/C8NJ04219E

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