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Living cell imaging and sensing of hydrogen sulfide using high-efficiency fluorescent Cu-doped carbon quantum dots

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Abstract

In this paper, we have presented a convenient strategy to fabricate Cu-doped carbon quantum dots (Cu-CQDs) for H2S sensing and imaging applications. Cu-CQDs are obtained by one step hydrothermal carbonization, using ethylenediaminetetraacetic acid salts and cupric chloride as sources, which simultaneously incorporates Cu (H2S-responding site) and a luminescent carbon quantum dot (fluorophore). Thus, the added NaHS (H2S donor) can lead to the fluorescence quenching of Cu-CQDs, and such a fluorescence response allows the detection of H2S in the range of 2–500 μM with a detection limit of 0.5 μM (S/N = 3). In addition, confocal imaging was achieved successfully in living cells.

Graphical abstract: Living cell imaging and sensing of hydrogen sulfide using high-efficiency fluorescent Cu-doped carbon quantum dots

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Publication details

The article was received on 05 Sep 2018, accepted on 26 Oct 2018 and first published on 31 Oct 2018


Article type: Paper
DOI: 10.1039/C8NJ03654C
Citation: New J. Chem., 2018, Advance Article
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    Living cell imaging and sensing of hydrogen sulfide using high-efficiency fluorescent Cu-doped carbon quantum dots

    S. Zhuo, L. Gao, P. Zhang, J. Du and C. Zhu, New J. Chem., 2018, Advance Article , DOI: 10.1039/C8NJ03654C

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